Managing extremely high triglycerides

People living with Familial Chylomicronemia Syndrome (FCS) should have their lipid levels checked at least once every 3 months or as necessary. 

Test frequently

According to the American Association of Clinical Endocrinology 
and the American College of Endocrinology consensus statement.

Scheduling regular triglyceride monitoring every 3 months, as necessary, is key to understanding your patient’s risk.

The National Lipid Association recommends that people with FCS adhere to a low-fat diet

Diet and meal planning are also important factors for managing extremely high triglycerides. Did you know that just one meal can spike triglyceride levels and increase the associated risk of acute pancreatitis?


We’ll get there [soon]

There are few options to keep triglycerides in check

For some people, traditional triglyceride-lowering therapies and intensive dieting are not enough to lower levels and reduce acute pancreatitis risk.

Show References

  1. Handelsman Y, Jellinger PS, Guerin CK, et al. Consensus statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the management of dyslipidemia and prevention of cardiovascular disease algorithm – 2020 executive summary. Endocr Pract. 2020;26(10):1196-1224. 
  2. Grundy SM, Stone NJ, Bailey AL, et al. 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA guideline on the management of blood cholesterol: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Circulation. 2019;139(25):e1046-e1081. 
  3. Javed F, Hegele R, Garg A, et al. Familial chylomicronemia syndrome: an expert clinical review from National Lipid Association. J Clin Lipidol. 2025;19(3):382-403.
  4. Goldberg RB, Chait A. A comprehensive update on the chylomicronemia syndrome. Front Endocrinol (Lausanne). 2020;11:593931.